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What is TRT? Testosterone Replacement Therapy (TRT) is a medical treatment aimed at restoring testosterone levels in individuals experiencing low testosterone, a condition known as hypogonadism. While TRT can offer significant benefits for men with confirmed hypogonadism, such as increased energy, libido, muscle mass, and bone density, it’s essential to approach with caution and under strict medical supervision. The underlying cause of low testosterone must be accurately diagnosed and addressed before initiating TRT. For instance, if low testosterone is a symptom of an underlying medical condition, treating the root cause might be more beneficial than TRT alone.